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Gene Expression Literature Summary
Assay
Age
In situ RNA (whole mount)
8.5 DPC

11 matching records from 11 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Tbx2  T-box 2  
Results  Reference
1J:136177 Barrionuevo F, Naumann A, Bagheri-Fam S, Speth V, Taketo MM, Scherer G, Neubuser A, Sox9 is required for invagination of the otic placode in mice. Dev Biol. 2008 May 1;317(1):213-24
1J:98516 Cai CL, Zhou W, Yang L, Bu L, Qyang Y, Zhang X, Li X, Rosenfeld MG, Chen J, Evans S, T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development. 2005 May;132(10):2475-87
1*J:53293 Chang H, Huylebroeck D, Verschueren K, Guo Q, Matzuk MM, Zwijsen A, Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects. Development. 1999 Apr;126(8):1631-42
1J:113522 Deng J, Dekruyff RH, Freeman GJ, Umetsu DT, Levy S, Critical role of CD81 in cognate T-B cell interactions leading to Th2 responses. Int Immunol. 2002 May;14(5):513-23
1*J:93610 Harrelson Z, Kelly RG, Goldin SN, Gibson-Brown JJ, Bollag RJ, Silver LM, Papaioannou VE, Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development. Development. 2004 Oct;131(20):5041-52
1J:113422 Harrelson Z, Papaioannou VE, Segmental expression of the T-box transcription factor, Tbx2, during early somitogenesis. Dev Dyn. 2006 Nov;235(11):3080-4
1*J:66591 Mahlapuu M, Ormestad M, Enerback S, Carlsson P, The forkhead transcription factor Foxf1 is required for differentiation of extra-embryonic and lateral plate mesoderm. Development. 2001 Jan;128(2):155-66
1J:154674 Shirai M, Imanaka-Yoshida K, Schneider MD, Schwartz RJ, Morisaki T, T-box 2, a mediator of Bmp-Smad signaling, induced hyaluronan synthase 2 and Tgfbeta2 expression and endocardial cushion formation. Proc Natl Acad Sci U S A. 2009 Nov 3;106(44):18604-9
1J:98806 Singh MK, Christoffels VM, Dias JM, Trowe MO, Petry M, Schuster-Gossler K, Burger A, Ericson J, Kispert A, Tbx20 is essential for cardiac chamber differentiation and repression of Tbx2. Development. 2005 Jun;132(12):2697-707
1J:332291 Song H, Morrow BE, Tbx2 and Tbx3 regulate cell fate progression of the otic vesicle for inner ear development. Dev Biol. 2022 Dec 12;494:71-84
1J:98489 Stennard FA, Costa MW, Lai D, Biben C, Furtado MB, Solloway MJ, McCulley DJ, Leimena C, Preis JI, Dunwoodie SL, Elliott DE, Prall OW, Black BL, Fatkin D, Harvey RP, Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development. 2005 May;132(10):2451-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/07/2024
MGI 6.23
The Jackson Laboratory